Problemas com move_upload_file

Galera estou usando um script para upload, mas ele não tá funcionando. esse é o script:

<?php include"../../Connections/config.php";

 $conexao = mysql_connect("$hostname_config", "$username_config", "$password_config")
 or die ("Erro ao conectar com o banco de dados.");
 $db = mysql_select_db("$database_config")
 or die ("Erro ao selecionar a base de dados.");

if (!empty($_FILES)) {
$id_album=$_GET['id_album'];

$targetFolder = '../../up/fotos';

chmod($targetFolder, 777);
 $imagem = $_FILES['Filedata'];
 $img=$imagem['name'];
 // Verifica a extensão do arquivo
 $extensao=substr($img, -3);
 if($extensao=="peg"){
 $extensao="jpeg";
 }

 $img = md5($img);
 $targetFile = $targetFolder . "/". $img.".".$extensao;

 // Validate the file type
 $fileTypes = array('jpg','jpeg','gif','png'); // File extensions
 $fileParts = pathinfo($imagem['tmp_name']);

 $data_atual=date('Y-m-d');

 if (in_array($extensao,$fileTypes)) {
 if(move_uploaded_file($imagem['tmp_name'],$targetFile)){
 echo '1';
 $inF = mysql_query("INSERT INTO fotos(img, data, id_album) VALUES ('$img','$data_atual','$id_album')") or die (mysql_error());
 }
 } else {
 echo 'Tipo de Imagem Invalida!';
 }
}

?>

E o Debug mostra isso:

SWF DEBUG: <b>Warning</b>: move_uploaded_file(../../up/fotos/d328ae2e509c9979c87835881b21d23c.jpg) [<a href='function.move-uploaded-file'>function.move-uploaded-file</a>]: failed to open stream: Permission denied in <b>/home/santo458/public_html/admin/uploadify/uploadify.php</b> on line <b>38</b><br />
SWF DEBUG: <br />
SWF DEBUG: <b>Warning</b>: move_uploaded_file() [<a href='function.move-uploaded-file'>function.move-uploaded-file</a>]: Unable to move '/tmp/phpMx9yGC' to '../../up/fotos/d328ae2e509c9979c87835881b21d23c.jpg' in <b>/home/santo458/public_html/admin/uploadify/uploadify.php</b> on line <b>38</b><br />